Characterization of hepatic pathology during azoxymethane-induced acute liver failure

Figure 2 Hepatic CYP2E1 expression is decreased during azoxymethane-induced liver injury. A: Relative CYP2E1 mRNA expression in liver homogenates from mice injected with vehicle or azoxymethane (AOM) at indicated time points; B: Representative immunoblot for CYP2E1 in vehicle and AOM-treated mice at the pre, minor, major and coma time points. β-Actin is used as a protein loading control; C: Quantification of relative CYP2E1 protein from immunoblots in liver homogenates from vehicle and AOM-treated mice at the pre, minor, major and time points. n ≥ 3 for each group for all analyses. ^aP < 0.05 compared to vehicle-treated mice.