scRNA-seq of the intestine reveals the key role of mast cells in early gut dysfunction associated with acute pancreatitis

Figure 1 Single-cell expression atlas of the small intestine in mice with acute pancreatitis. A: Modeling procedure for AP1 and AP2 in mice; B: HE staining of the pancreas in the AP1, AP2 and normal group; C: Workflow for the collection and processing of specimens from AP1, AP2, and control small intestine samples for scRNA-seq; D: Cell type and number ratio identified by single-cell sequencing; E: UMAP plot illustrating major cell types in the small intestine of mice; F: Heatmap showing the expression levels of specific markers in each cell type of the small intestine; G: Violin plots displaying the expression of representative well-known markers across identified cell types in the small intestine.