Diagnostic yield of follow-up in patients undergoing surgery for non-metastatic colorectal cancer

Table 4 Risk factors for death at 5-year follow-up, n (%)

	All-cause mortality		P value	Multivariate analysis, OR (95%CI)	P value	CCR mortality		P value	Multivariate analysis, OR (95%CI)	P value
	Yes	No				Yes	No
Sex
Male	144 (41.5)	203 (58.5)	0.9			61 (17.6)	286 (82.4)	0.7
Female	93 (41.0)	134 (59.0)				37 (16.3)	190 (83.7)
Average age	75.3	66.3	< 0.001	0.93 (0.91-0.95)	< 0.001	71.5	66.3	< 0.001	0.97 (0.94-0.99)	0.05
TNM stage
I-II	125 (35.4)	228 (64.6)	< 0.001	0.38 (0.24-0.61)	< 0.001	34 (9.6)	319 (90.4)	< 0.001	0.26 (0.15-0.46)	< 0.001
III	112 (50.7)	109 (49.3)		1		64 (29.0)	157 (71.0)		1
Location
Right hemicolon	84 (44.7)	104 (55.3)	0.25			29 (15.4)	159 (84.6)	0.46
Left hemicolon	153 (39.6)	233 (60.4)				69 (17.9)	317 (82.1)
Surgery
Laparoscopy	42 (31.6)	91 (68.4)	0.01	0.72 (0.44-1.17)	0.19	17 (12.8)	116 (87.2)	0.13	0.68 (0.36-1.27)	0.22
Laparotomy	195 (44.2)	246 (55.8)		1		81 (18.4)	360 (81.6)		1
Perioperative complications
Yes	36 (51.4)	34 (48.6)	0.07	1.14 (0.62-2.09)	0.68	20 (28.6)	50 (71.4)	0.01	1.72 (0.91-3.27)	0.1
No	201 (39.9)	303 (60.1)		1		78 (15.5)	426 (84.5)		1
Postoperative complications
Yes	113 (51.6)	106 (48.4)	< 0.001	1.41 (0.93-2.14)	0.1	42 (19.2)	117 (80.8)	0.29	1.25 (0.72-2.04)	0.37
No	124 (34.9)	231 (65.1)		1		56 (15.8)	299 (84.2)		1
Adjuvant chemotherapy
Yes	71 (34.3)	136 (65.7)	0.01	1.04 (0.64-1.74)	0.84	50 (26.9)	136 (73.1)	0.06	1.60 (0.95-2.72)	0.08
No	166 (45.2)	201 (54.8)		1		48 (19.3)	201 (80.7)		1
Neoadjuvant chemo-radiotherapy
Yes	21 (29.6)	50 (70.4)	0.03	1.14 (0.61-2.31)	0.69	12 (19.4)	50 (80.6)	0.518
No	216 (42.9)	287 (57.1)		1		86 (23.1)	287 (76.9)
Adherence to follow-up recommendations
Yes	62 (21.6)	225 (78.4)	< 0.001	0.30 (0.20-0.46)	< 0.001	32 (12.5)	225 (87.5)	< 0.001	0.35 (0.21-0.59)	< 0.001
No	141 (55.7)	112 (44.3)		1		65 (36.7)	112 (63.3)		1

CT: Computed tomography; OR: Odds ratio; TNM: Tumor-node-metastasis; CCR: Colorectal cancer.