Trichostatin A augments cell migration and epithelial-mesenchymal transition in esophageal squamous cell carcinoma through BRD4/c-Myc endoplasmic reticulum-stress pathway

Figure 6 Expression of acetylated histones H3 is higher in esophageal squamous cell carcinoma than in paracancerous tissues, and acH3 was an independent factor affecting prognosis. A: Representative detection of acetylated histones H3 (acH3) level in esophageal squamous cell carcinoma (ESCC) by western blot, N means adjacent tissues and C means cancer tissues; B: Statistical analysis of 43 cases of ESCC showed that the level of acH3 in ESCC tumor tissue was 1.66 times higher than that in adjacent tissue; C: Kaplan-Meier survival curve of the relationship between acH3 expression and prognosis in patients with esophageal carcinoma. P vs control. ^bP < 0.01. NC: Negative control; acH3: Acetylated histones H3.