Apatinib regulates the glycolysis of vascular endothelial cells through PI3K/AKT/PFKFB3 pathway in hepatocellular carcinoma

doi:10.3748/wjg.v31.i11.102848

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Mar 21, 2025 (publication date) through Apr 21, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 21, 2025; 31(11): 102848
Published online Mar 21, 2025. doi: 10.3748/wjg.v31.i11.102848

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Figure 8 A schematic illustrating the impact of apatinib on glycolysis in vascular endothelial cells. VEGF: Vascular endothelial growth factor; PI3K: Phosphatidylinositol 3-kinase; ATP: Adenosine triphosphate; ADP: Adenosine diphosphate; HCC: Hepatocellular carcinoma.

Citation: Wu Y, Xie BB, Zhang BL, Zhuang QX, Liu SW, Pan HM. Apatinib regulates the glycolysis of vascular endothelial cells through PI3K/AKT/PFKFB3 pathway in hepatocellular carcinoma. World J Gastroenterol 2025; 31(11): 102848
URL: https://www.wjgnet.com/1007-9327/full/v31/i11/102848.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i11.102848