Preoperative prediction of textbook outcome in intrahepatic cholangiocarcinoma by interpretable machine learning: A multicenter cohort study

doi:10.3748/wjg.v31.i11.100911

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 31, Issue 11

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (954)

All Articles published online

The chart showing PDF series, HTML series, Figures (1-6) series, Tables (1-3) series.

Item

Count

PDF

HTML

645

Figures (1-6)

Tables (1-3)

Sum=838

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

Download

Sum=81

Mar 21, 2025 (publication date) through Apr 3, 2025

Times Cited of This Article

Times Cited (0)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Gastroenterol. Mar 21, 2025; 31(11): 100911
Published online Mar 21, 2025. doi: 10.3748/wjg.v31.i11.100911

Table 2 Baseline characteristics of patients in validation group, n (%)

Variables	Total (n = 89)	Textbook outcome (n = 49)	None-textbook outcome (n = 40)	P value
Age, M (Q₁, Q₃)	58.00 (48.00, 65.00)	59.00 (53.00, 64.00)	56.50 (46.75, 65.00)	0.501
Sex				0.167
Male	53 (59.55)	26 (53.06)	27 (67.50)
Female	36 (40.45)	23 (46.94)	13 (32.50)
Hepatitis B				0.190
Negative	64 (71.91)	38 (77.55)	26 (65.00)
Positive	25 (28.09)	11 (22.45)	14 (35.00)
ECOG score				0.001
0	32 (35.96)	25 (51.02)	7 (17.50)
1	57 (64.04)	24 (48.98)	33 (82.50)
Child-Pugh				0.017
A	57 (64.04)	26 (53.06)	31 (77.50)
B	32 (35.96)	23 (46.94)	9 (22.50)
Tumor size, M (Q₁, Q₃)	6.50 (5.00, 8.40)	6.70 (4.70, 8.40)	6.50 (5.00, 8.27)	0.853
Tumor number				0.104
Solitary	66 (74.16)	33 (67.35)	33 (82.50)
Multiple	23 (25.84)	16 (32.65)	7 (17.50)
TBIL, M (Q₁, Q₃)	17.20 (10.70, 33.10)	19.00 (10.60, 41.50)	16.00 (11.18, 28.75)	0.668
DBIL, M (Q₁, Q₃)	7.90 (4.60, 12.70)	8.90 (5.10, 12.70)	6.45 (4.33, 12.25)	0.203
CA19-9, M (Q₁, Q₃)	109.10 (13.90, 778.00)	192.70 (17.60, 1000.00)	83.95 (8.10, 485.52)	0.073
AFP, M (Q₁, Q₃)	6.20 (2.70, 97.60)	5.10 (2.40, 97.60)	6.95 (2.70, 74.53)	0.738
CEA, M (Q₁, Q₃)	2.70 (1.80, 4.79)	2.50 (1.70, 3.70)	3.10 (2.00, 10.67)	0.030
Blood transfusion				0.008
No	82 (92.13)	49 (100.00)	33 (82.50)
Yes	7 (7.87)	0 (0.00)	7 (17.50)
Surgical margins				0.008
Negative	82 (92.13)	49 (100.00)	33 (82.50)
Positive	7 (7.87)	0 (0.00)	7 (17.50)
Complications				< 0.001
No	70 (78.65)	49 (100.00)	21 (52.50)
Yes	19 (21.35)	0 (0.00)	19 (47.50)
Perioperative death or readmission within 30 days after discharge				0.08
No	85 (95.51)	48 (100.00)	37 (90.00)
Yes	4 (4.49)	0 (0.00)	4 (10.00)
Prolonged hospitalization				< 0.001
No	57 (64.04)	49 (100.00)	8 (20.00)
Yes	32 (35.96)	0 (0.00)	32 (80.00)

M: Median; Q₁: 1^st quartile; Q₃: 3^st quartile; ECOG score: Eastern Cooperative Oncology Group score; TBIL: Total bilirubin; DBIL: Direct bilirubin; CA19-9: Carbohydrate antigen 19-9; AFP: Alpha-fetoprotein; CEA: Carcinoembryonic antigen.

Citation: Huang TF, Luo C, Guo LB, Liu HZ, Li JT, Lin QZ, Fan RL, Zhou WP, Li JD, Lin KC, Tang SC, Zeng YY. Preoperative prediction of textbook outcome in intrahepatic cholangiocarcinoma by interpretable machine learning: A multicenter cohort study. World J Gastroenterol 2025; 31(11): 100911
URL: https://www.wjgnet.com/1007-9327/full/v31/i11/100911.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i11.100911