Circular RNA contributes to gastric cancer by targeting Wnt family member 2B as a competing endogenous RNA

Figure 2 Hsa_circular-RNA_102415 silencing reduces gastric cancer cell proliferation and invasion and promotes apoptosis. Transfect small interfering-hsa_circular-RNA_102415 and control in BGC823 cells and AGS cells for 24 hours. A: Analyzed the relationship between gastric cancer cells and small interfering-hsa_circular-RNA_102415 using quantitative real-time polymerase chain reaction; B and C: Studied and analyzed the proliferation of cells transfected with cell counting kit-8; D and E: Studied and analyzed the invasion ability of cells after transfection using Transwell method; F and G: Used flow cytometry to study and analyze the level of apoptosis after cell transfection; H and I: Studied and analyzed the percentage of different cell cycle stages after cell transfection using flow cytometry. Data were reported using mean ± SEM (n = 3). ^bP < 0.001. circRNA: Circular RNA; si-NC: Small interfering negative control; FITC: Fluorescein isothiocyanate; OD: Optical density.