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©The Author(s) 2025.
World J Gastroenterol. Mar 14, 2025; 31(10): 103716
Published online Mar 14, 2025. doi: 10.3748/wjg.v31.i10.103716
Published online Mar 14, 2025. doi: 10.3748/wjg.v31.i10.103716
Table 4 The association between mt12361 and steatotic liver disease in the diabetes and non-diabetic subgroups
CMRF | Diabetes | Non-diabetes | ||||||||
mt12361 | χ2 | Trend test | mt12361 | χ2 | Trend test | |||||
A (%) | G (%) | P value | OR (95%CI) | P value | A (%) | G (%) | P value | OR (95%CI) | P value | |
4-5 | 28 (96.6) | 1 (3.4) | 1.000 | 1.11 (0.07-18.55) | 0.926 | 103 (92.8) | 8 (7.2) | 1.8 × 10-4 | 4.93 (1.97-12.35) | 5.3 × 10-5 |
2-3 | 8 (80.0) | 2 (20.0) | 0.136 | 7.75 (0.62-96.63) | 245 (95.0) | 13 (5.0) | 1.6 × 10-3 | 3.37 (1.52-7.48) | ||
0-1 | 31 (96.9) | 1 (3.1) | Ref. | Ref. | 762 (98.4) | 12 (1.6) | Ref. | Ref. | ||
3-5 | 32 (94.1) | 2 (5.9) | 1.000 | 1.81 (0.16-21.06) | 0.676 | 212 (93.8) | 14 (6.2) | 3.9 × 10-4 | 3.90 (1.74-8.71) | 5.6 × 10-4 |
1-2 | 6 (85.7) | 1 (14.3) | 0.347 | 4.83 (0.26-88.53) | 249 (96.9) | 8 (3.1) | 0.167 | 1.90 (0.75-4.77) | ||
0 | 29 (96.7) | 1 (3.3) | Ref. | Ref. | 649 (98.3) | 11 (1.7) | Ref. | Ref. | ||
3-5 | 32 (94.1) | 2 (5.9) | 1.000 | 1.09 (0.15-8.23) | 0.931 | 212 (93.8) | 14 (6.2) | 9.2 × 10-4 | 3.12 (1.54-6.33) | 9.2 × 10-4 |
0-2 | 35 (94.6) | 2 (5.4) | Ref. | Ref. | 898 (97.9) | 19 (2.1) | Ref. | Ref. |
- Citation: Lu MY, Wei YJ, Wang CW, Liang PC, Yeh ML, Tsai YS, Tsai PC, Ko YM, Lin CC, Chen KY, Lin YH, Jang TY, Hsieh MY, Lin ZY, Huang CF, Huang JF, Dai CY, Chuang WL, Yu ML. Mitochondrial mt12361A>G increased risk of metabolic dysfunction-associated steatotic liver disease among non-diabetes. World J Gastroenterol 2025; 31(10): 103716
- URL: https://www.wjgnet.com/1007-9327/full/v31/i10/103716.htm
- DOI: https://dx.doi.org/10.3748/wjg.v31.i10.103716