Nab-paclitaxel plus capecitabine as a first-line regimen for advanced biliary tract cancers: Feasible or not feasible?

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Mar 14, 2025 (publication date) through Feb 26, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 14, 2025; 31(10): 100771
Published online Mar 14, 2025. doi: 10.3748/wjg.v31.i10.100771

Table 2 Published results of nab-paclitaxel combination chemotherapy

Ref.	Regimen	Median OS (months)	Median PFS (months)	ORR (%)	DCR (%)	n
Shroff et al[8], 2019	Nab-paclitaxel + gemcitabine + cisplatin	19.2	11.8	45	84	60
Zhang et al[9], 2023	Nab-paclitaxel + S-1	13.2	6	27.5	70.6	54
Pressiani et al[10], 2024	Nab-paclitaxel + gemcitabine + oxaliplatin	12.4	6.3	20.89	67.15	67
Xu et al[5], 2024	Nab-paclitaxel + capecitabine	14.1	4.4	23.26	69.77	44

OS: Overall survival; PFS: Progression-free survival; ORR: Objective response rate; DCR: Disease control rate.

Citation: Chen JQ, Lan X. Nab-paclitaxel plus capecitabine as a first-line regimen for advanced biliary tract cancers: Feasible or not feasible? World J Gastroenterol 2025; 31(10): 100771
URL: https://www.wjgnet.com/1007-9327/full/v31/i10/100771.htm
DOI: https://dx.doi.org/10.3748/wjg.v31.i10.100771