Loss-of-function mutations of microRNA-142-3p promote ASH1L expression to induce immune evasion and hepatocellular carcinoma progression

Figure 8 ASH1L promotes an immunosuppressive microenvironment in hepatocellular carcinoma. A: Volcano plot of differentially expressed genes between high and low ASH1L groups; B: Kyoto encyclopedia of genes and genomes; C: Gene ontology pathway enrichment between high and low ASH1L groups; D: Correlation between ASH1L expression and 28 immune cell infiltration in the cancer genome atlas-liver hepatocellular carcinoma; E: Correlation between ASH1L expression and 28 immune cell infiltration in international cancer genome consortium, GSE76427 and GSE14520. MDSC: Myeloid-derived suppressor cell; GO: Gene ontology; KEGG: Kyoto encyclopedia of genes and genomes; CD: Cluster of differentiation; ICGC: International cancer genome consortium.