sTREM-1 as promising prognostic biomarker for acute-on-chronic liver failure and mortality in patients with acute decompensation of cirrhosis

Figure 3 Acute-on-chronic liver failure risk score associated with acute-on-chronic liver failure development in cirrhosis with acute decompensation. A: In bacterial infections (BI) or non-BI group, Soluble triggering receptor expressed on myeloid cell-1 Levels at admission were higher in patients with acute-on-chronic liver failure (ACLF) than those without; B: Prediction development of ACLF during 28-d follow-up for patients with acute decompensation according to ACLF risk score (ACLF-R) and other models; C: Calibration plot comparing the observed and predicted probabilities of ACLF from the Kaplan-Meier and ACLF-R. ^cP < 0.001. sTREM-1: Soluble triggering receptor expressed on myeloid cell-1; ACLF: Acute-on-chronic liver failure score; BI: Bacterial infections; ACLF-R: Acute-on-chronic liver failure risk score; P-AD: Prognostic model of acute decompensation; MELD: Model for end-stage liver disease; CLIF-C: Chronic liver failure-consortium; CLIF-C AD: Chronic liver failure-consortium acute decompensation score; CLIF-C ACLF: Chronic liver failure-consortium acute-on-chronic liver failure score.