Mitochondrial dysfunction affects hepatic immune and metabolic remodeling in patients with hepatitis B virus-related acute-on-chronic liver failure

Figure 2 Expression of hypoxia-inducible factor-1α increased in the liver tissues of patients with acute-on-chronic liver failure. A: Immunohistochemical staining of hypoxia-inducible factor-1α (HIF-1α); B: Semi-quantitative analysis of HIF-1α expression. Data were compared using unpaired student’s t-test. ACLF: Acute-on-chronic liver failure; HD: Healthy donor; HIF-1α: Hypoxia-inducible factor-1α.