Diagnostic and therapeutic role of endoscopic ultrasound in liver diseases: A systematic review and meta-analysis

Table 3 Characteristics of studies on the therapeutic role of endoscopic ultrasound

Ref.	Study design	Study location	Participant characteristics		Condition	Intervention	Outcomes
			Sample (n)	M/F
Ogura et al[35], 2016	Retrospective study	Japan	27	20/7	Liver abscess	EUS-AD	Clinical success: 100%
							Technical success: 100%
							Complications: None
Tanikawa et al[36], 2023	Retrospective study	Japan	8	4/4	Liver abscess	EUS-AD	Clinical success: 87.5%
							Technical success: 87.5%
Tonozuka et al[37], 2015	Retrospective case series	Japan		NR	Liver abscess	EUS-AD	Clinical success: 100%
							Technical success: 100%
							Complications: None
Carbajo et al[38], 2019	Retrospective study	Spain	9	NR	Liver abscess	EUS-AD	Clinical success: 88.9%
							Technical success: 88.9%
Nakaji et al[39], 2016	Retrospective study	Japan	12	10/2	Solid liver lesions	EUS-guided ethanol injection	Complications: 2
							Overall survival: 91.7%, 75%, and 53.3% at 1, 2, and 3 years
Jiang et al[52], 2016	Case series	China	26	17/9	Solid liver lesions	EUS-guided ethanol injection and iodine-125 brachytherapy	Complications: None
Frost et al[40], 2018	Case series	Ireland	8	7/1	GV	EUS-guided thrombin injection	Complications: None
							Obliteration: 75%
							Rebleeding: 1 patient
Bhat et al[41], 2016	Retrospective study	United States	152	97/55	GV	EUS-guided CYA and coil embolization	Technical success: 99%
							Obliteration: 93%
							Rebleeding: 20 patients
							Complications: 9 patients
Bick et al[42], 2019	Retrospective study	United States	104	62/42	GV	EUS-guided CYA	Obliteration: 79%
							Rebleeding: 12 patients
							Complications: 13 patients
Binmoeller et al[43], 2011	Retrospective study	United States	30	19/11	GV	EUS-guided CYA and coil embolization	Technical success: 100%
							Obliteration: 95.8%
							Rebleeding: 4 patients
							Complications: None
Bazarbashi et al[44], 2020	Prospective study	United States	40	27/13	GV	EUS-Guided coil embolization	Technical success: 100%
							Obliteration: 100%
							Complications: 1 patient
Lôbo et al[53], 2019	RCT	Brazil	32	13/19	GV	EUS-guided CYA and coil embolization	Complications: 13 patients
							Obliteration: 93.3%
Mukkada et al[45], 2018	Retrospective study	India	30	NR	GV	EUS-Guided coil embolization	Rebleeding: 6 patients
Lee et al[46], 2000	Prospective study	China	101	69/32	GV	EUS-guided CYA	Obliteration: 79.6%
							Complications: 22 patients
							Rebleeding: 19 patients
Gubler et al[47], 2014	Retrospective study	Switzerland	40	25/15	GV	EUS-guided CYA	Complications: 2 patients
Kozieł et al[48], 2019	Retrospective study	Poland	16	9/7	GV	EUS-guided CYA and coil embolization	Technical success: 94%
							Complications: 6 patients
Romero-Castro et al[49], 2013	Retrospective study	Germany	30	22/8	GV	EUS-guided coil embolization	Obliteration: 90.9%
							Complications: 1 patient
							Rebleeding: None

M/F: Male/female; NR: Not report; RCT: Randomized clinical trial; EUS-AD: Endoscopic ultrasound guided liver abscess drainage; GV: Gastric varices; CYA: Cyanoacrylate.