Development and validation of a prediction model for early screening of people at high risk for colorectal cancer

Figure 4 Decision curve analysis for predicting early screening of individuals at high risk of colorectal cancer. A: Decision curve analysis (DCA) of the validation set prediction model; B: DCA of the training set prediction model. Red solid lines indicate the prediction models, gray solid lines indicate all populations at high risk for colorectal cancer (CRC), and solid horizontal lines indicate non-high-risk populations for CRC. The graph depicts the expected net gain for each individual relative to the high-risk CRC Nuo plot forecast. Net gain increases with the model curve.