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©The Author(s) 2024.
World J Gastroenterol. Dec 28, 2024; 30(48): 5130-5151
Published online Dec 28, 2024. doi: 10.3748/wjg.v30.i48.5130
Published online Dec 28, 2024. doi: 10.3748/wjg.v30.i48.5130
Table 2 Association between systemic immune-inflammation index/albumin and clinicopathological characteristics, n (%)
| Characteristics | Systemic immune-inflammation index/albumin | P value | |
| Low (n = 1142) | High (n = 511) | ||
| Sex | 0.424 | ||
| Female | 176 (15.4) | 71 (13.9) | |
| Male | 966 (84.6) | 440 (86.1) | |
| Age, years | 0.503 | ||
| ≤ 60 | 813 (71.2) | 372 (72.8) | |
| > 60 | 329 (28.8) | 139 (27.2) | |
| Hepatitis B surface antigen | < 0.001 | ||
| Negative | 151 (13.2) | 112 (21.9) | |
| Positive | 991 (86.8) | 399 (78.1) | |
| Alpha-fetoprotein, ng/mL | 0.945 | ||
| < 400 | 946 (82.8) | 424 (83.0) | |
| ≥ 400 | 196 (17.2) | 87 (17.0) | |
| Platelets, 109/L | < 0.001 | ||
| > 100 | 684 (59.9) | 494 (96.7) | |
| ≤ 100 | 458 (40.1) | 17 (3.3) | |
| Neutrophil, 109/L | < 0.001 | ||
| ≤ 6.3 | 1135 (99.4) | 442 (86.5) | |
| > 6.3 | 7 (0.6) | 69 (13.5) | |
| Lymphocyte, 109/L | 0.358 | ||
| > 0.8 | 69 (6.0) | 37 (7.2) | |
| ≤ 0.8 | 1073 (94.0) | 474 (92.8) | |
| Alanine transaminase, U/L | 0.579 | ||
| ≤ 40 | 833 (72.9) | 366 (71.6) | |
| > 40 | 309 (27.1) | 145 (28.4) | |
| Aspartate transaminase, U/L | < 0.001 | ||
| ≤ 40 | 718 (62.9) | 248 (48.5) | |
| > 40 | 424 (37.1) | 263 (51.5) | |
| Prothrombin time, second | 0.022 | ||
| ≤ 13 | 956 (83.7) | 404 (79.1) | |
| > 13 | 186 (16.3) | 107 (20.9) | |
| Total bilirubin, μmol/L | 0.686 | ||
| ≤ 32.4 | 1127 (98.7) | 503 (98.4) | |
| > 32.4 | 15 (1.3) | 8 (1.6) | |
| Albumin, g/L | < 0.001 | ||
| > 35 | 1108 (97.0) | 464 (90.8) | |
| ≤ 35 | 34 (3.0) | 47 (9.2) | |
| Albumin-bilirubin grade | < 0.001 | ||
| 1 | 937 (82.0) | 342 (66.9) | |
| 2 | 205 (18.0) | 169 (33.1) | |
| Tumor diameter, cm | < 0.001 | ||
| < 5 | 654 (57.3) | 131 (25.6) | |
| ≥ 5 | 488 (42.7) | 380 (74.4) | |
| Number of tumors | 0.353 | ||
| Single | 966 (84.6) | 423 (82.8) | |
| Multiple | 176 (15.4) | 88 (17.2) | |
| Barcelona Clinic Liver Cancer stage | < 0.001 | ||
| 0 | 128 (11.2) | 24 (4.7) | |
| A | 837 (73.3) | 355 (69.5) | |
| B | 110 (9.6) | 74 (14.5) | |
| C | 67 (5.9) | 58 (11.4) | |
| Hypertension | 0.784 | ||
| No | 967 (84.7) | 430 (84.1) | |
| Yes | 175 (15.3) | 81 (15.9) | |
| Diabetes | 0.595 | ||
| No | 1046 (91.6) | 472 (92.4) | |
| Yes | 96 (8.4) | 39 (7.6) | |
| Cardiovascular disease | 0.409 | ||
| No | 1124 (98.4) | 500 (97.8) | |
| Yes | 18 (1.6) | 11 (2.2) | |
| Anatomical resection | < 0.001 | ||
| No | 769 (67.3) | 299 (58.5) | |
| Yes | 373 (32.7) | 212 (41.5) | |
| Major hepatectomy | < 0.001 | ||
| No | 1034 (90.5) | 381 (74.6) | |
| Yes | 108 (9.5) | 130 (25.4) | |
| Transfusion | < 0.001 | ||
| No | 1099 (96.2) | 458 (89.6) | |
| Yes | 43 (3.8) | 53 (10.4) | |
| Differentiation | < 0.001 | ||
| I-II | 664 (58.1) | 234 (45.8) | |
| III-IV | 478 (41.9) | 277 (54.2) | |
| Microvascular invasion | < 0.001 | ||
| No | 864 (75.7) | 313 (61.3) | |
| Yes | 278 (24.3) | 198 (38.7) | |
| Cirrhosis | < 0.001 | ||
| No | 466 (40.8) | 329 (64.4) | |
| Yes | 676 (59.2) | 182 (35.6) | |
| Portal vein tumor thrombus | < 0.001 | ||
| No | 1075 (94.1) | 453 (88.6) | |
| Yes | 67 (5.9) | 58 (11.4) | |
- Citation: Chen KL, Qiu YW, Yang M, Wang T, Yang Y, Qiu HZ, Sun T, Wang WT. Prognostic value of preoperative systemic immune-inflammation index/albumin for patients with hepatocellular carcinoma undergoing curative resection. World J Gastroenterol 2024; 30(48): 5130-5151
- URL: https://www.wjgnet.com/1007-9327/full/v30/i48/5130.htm
- DOI: https://dx.doi.org/10.3748/wjg.v30.i48.5130