Multi-clustering study on the association between human leukocyte antigen-DP-DQ and hepatitis B virus-related hepatocellular carcinoma and cirrhosis in Viet Nam

Table 3 Correlation of human leukocyte antigen-DP and human leukocyte antigen-DQ polymorphisms with the risk of hepatitis B virus-related liver cirrhosis and hepatocellular carcinoma

SNPs	CHB vs HBV-related LC		CHB vs HBV-related HCC		HBV-related LC vs HBV-related HCC
	OR (95%CI)	P value	OR (95%CI)	P value	OR (95%CI)	P value
rs2856718
GG	1		1		1
AG	0.807 (0.572-1.139)	0.2219	1.138 (0.808-1.602)	0.4601	1.410 (0.952-2.089)	0.0865
AA	0.019 (0.670-1.549)	0.9307	1.006 (0.647-1.564)	0.9795	0.976 (0.598-1.594)	0.9224
AA + AG	0.871 (0.637-1.193)	0.3891	1.094 (0.794-1.508)	0.5813	1.257 (0.874-1.806)	0.2170
G allele	1		1		1
A allele	0.986 (0.791-1.230)	0.9011	1.029 (0.826-1.282)	0.7984	1.044 (0.811-1.342)	0.7396
rs3077
GG	1		1		1
AG	1.049 (0.763-1.442)	0.7673	0.694 (0.501-0.961)	0.0278	0.661 (0.457-0.957)	0.0284
AA	0.994 (0.514-1.921)	0.9859	0.837 (0.435-1.612)	0.5949	0.842 (0.397-1.789)	0.6548
AA + AG	1.042 (0.767-1.416)	0.7924	0.712 (0.522-0.972)	0.0324	0.683 (0.479-0.974)	0.0352
G allele	1		1		1
A allele	1.027 (0.805-1.310)	0.8305	0.791 (0.613-1.02)	0.0705	0.775 (0.582-1.032)	0.0810
rs9277535
GG	1		1		1
AG	0.984 (0.715-1.354)	0.9204	0.840 (0.610-1.159)	0.2883	0.854 (0.591-1.235)	0.4022
AA	2.797 (1.168-6.702)	0.0210	1.786 (0.694-4.593)	0.2290	0.638 (0.265-1.539)	0.3174
AA + AG	1.067 (0.783-1.455)	0.6814	0.884 (0.646-1.209)	0.4393	0.828 (0.580-1.183)	0.3001
G allele	1		1		1
A allele	1.148 (0.888-1.484)	0.2924	0.962 (0.739-1.254)	0.7759	0.838 (0.623-1.128)	0.2438

CHB: Chronic Hepatitis B virus; HBV: Hepatitis B virus; HCC: Hepatocellular carcinoma; LC: Liver cirrhosis; SNP: Single nucleotide polymorphism.