Multi-clustering study on the association between human leukocyte antigen-DP-DQ and hepatitis B virus-related hepatocellular carcinoma and cirrhosis in Viet Nam

doi:10.3748/wjg.v30.i46.4880

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Dec 14, 2024 (publication date) through Apr 12, 2025

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Dec 14, 2024; 30(46): 4880-4903
Published online Dec 14, 2024. doi: 10.3748/wjg.v30.i46.4880

Table 1 Clinical characteristics of study subjects

Variable		Healthy control (n = 315)	CHB (n = 471)	HBV-related LC (n = 250)	HBV-related HCC (n = 251)	HBV carrier (n = 972)
Age, mean ± SD		52.78 ± 11.63	50.43 ± 14.67	54.75 ± 13.36	55.99 ± 9.91	52.98 ± 13.48
Age	< 60	237	353	165	165
Age	≥ 60	78	118	85	86
Gender	Male	244	367	190	212	769
Gender	Female	71 (22.5)	104 (22.1)	60 (24.0)	39 (15.5)	203 (20.9)
ALT		24.92 ± 11.93	87.79 ± 168.66	388.67 ± 442.21	73.19 ± 73.53
AST		24.91 ± 7.68	70.89 ± 112.36	362.19 ± 401.41	87.89 ± 177.25

ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; CHB: Chronic Hepatitis B virus; HBV: Hepatitis B virus; HCC: Hepatocellular carcinoma; LC: Liver cirrhosis.

Citation: Nguyen TT, Ho TC, Bui HTT, Tran VK, Nguyen TT. Multi-clustering study on the association between human leukocyte antigen-DP-DQ and hepatitis B virus-related hepatocellular carcinoma and cirrhosis in Viet Nam. World J Gastroenterol 2024; 30(46): 4880-4903
URL: https://www.wjgnet.com/1007-9327/full/v30/i46/4880.htm
DOI: https://dx.doi.org/10.3748/wjg.v30.i46.4880