Validation of prognostic scores for predicting acute liver failure and in-hospital death in patients with dengue-induced severe hepatitis

Table 2 Parameters at initial presentation

Parameter	All DISH patients (n = 198)	DISH without ALF (n = 174)	DISH with ALF (n = 24)	P value
Laboratory profiles
WBC count (103/L)	5.52 ± 3.85	5.24 ± 3.63	7.48 ± 4.78	0.007
Neu (103/L)	3.20 ± 2.78	2.99 ± 2.73	4.53 ± 2.86	0.021
INR	1.38 ± 0.64	1.16 ± 0.25	2.42 ± 0.85	< 0.001
Cr (mg/dL)	1.04 ± 1.01	0.91 ± 0.89	1.93 ± 1.30	< 0.001
Albumin (g/dL)	3.60 ± 0.54	3.69 ± 0.49	3.09 ± 0.55	< 0.001
TB (mg/dL)	1.95 ± 4.34	1.28 ± 1.54	6.34 ± 10.44	< 0.001
SGOT (U/L)	1515.86 ± 2258.05	1031.51 ± 1195.21	5007.25 ± 4275.91	< 0.001
SGPT (U/L)	683.64 ± 749.00	550.41 ± 458.53	1649.54 ± 1454.57	< 0.001
Liver prognostic scores
MELD score	12.20 ± 8.01	9.52 ± 4.46	24.71 ± 9.05	< 0.001
EZ-ALBI score	-30.27 ± 7.48	-31.81 ± 4.99	-20.95 ± 12.17	< 0.001
ALBI score	-2.17 ± 0.68	-2.29 ± 0.62	-1.48 ± 0.62	< 0.001
PALBI score	-1.06 ± 0.53	-1.15 ± 0.49	-0.61 ± 0.47	< 0.001

DISH: Dengue-induced severe hepatitis; ALF: Acute liver failure; WBC: White blood cell; Neu: Neutrophils; INR: International normalized ratio; Cr: Creatinine; TB: Total bilirubin; SGOT: Serum glutamate-oxaloacetate transaminase; SGPT: Serum glutamate-pyruvate transaminase; MELD: Model for end-stage liver disease; ALBI: Albumin-bilirubin; EZ-ALBI: Easy albumin-bilirubin; PALBI: Platelet-albumin-bilirubin.