Recurrence and influencing factors of hepatitis B surface antigen seroclearance induced by peginterferon alpha-based regimens

doi:10.3748/wjg.v30.i44.4725

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Nov 28, 2024 (publication date) through Apr 12, 2025

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Nov 28, 2024; 30(44): 4725-4737
Published online Nov 28, 2024. doi: 10.3748/wjg.v30.i44.4725

Table 3 Multivariate logistic regression analysis of predictors of hepatitis B surface antigen recurrence

Characteristics	OR	95%CI	P value
Age (years)	0.924	(0.843-1.012)	0.089
Gender	0.665	(0.140-3.169)	0.609
Peg-IFN-α-2a	0.759	(0.165-3.485)	0.723
Without HBsAg seroconversion	9.388	(0.512-172.212)	0.131
HBsAb < 35.3 mIU/mL	3.449	(0.264-45.112)	0.345
Consolidation time < 12 weeks	28.044	(4.525-173.791)	< 0.001
HBsAb disappeared during the follow-up	46.445	(2.571-838.957)	0.009

Peg-IFN-α: Peginterferon alpha; HBsAg: Hepatitis B surface antigen; HBsAb: Hepatitis B surface antibody; OR: Odds ratio.

Citation: Lu R, Zhang M, Liu ZH, Hao M, Tian Y, Li M, Wu FP, Wang WJ, Shi JJ, Zhang X, Jia XL, Jiang ZC, Li XM, Xu GH, Li YP, Dang SS. Recurrence and influencing factors of hepatitis B surface antigen seroclearance induced by peginterferon alpha-based regimens. World J Gastroenterol 2024; 30(44): 4725-4737
URL: https://www.wjgnet.com/1007-9327/full/v30/i44/4725.htm
DOI: https://dx.doi.org/10.3748/wjg.v30.i44.4725