Observational Study
Copyright ©The Author(s) 2024.
World J Gastroenterol. Nov 28, 2024; 30(44): 4725-4737
Published online Nov 28, 2024. doi: 10.3748/wjg.v30.i44.4725
Table 2 Univariate logistic regression analysis of the predictors of hepatitis B surface antigen recurrence
Characteristics
OR
95%CI
P value
Age (years)0.962(0.916-1.012)0.133
Gender1.692(0.588-4.870)0.329
Family history of HBV infection0.655(0.227-1.890)0.434
Characteristics at the initiation of peg-IFN-α
HBsAg level, IU/mL1.000(1.000-1.000)0.398
HBsAb negative0.933(0.107-8.130)0.950
HBV DNA positive0.514(0.176-1.506)0.225
HBeAg positive1.448(0.302-6.934)0.643
Peg-IFN-α-2a1.624(0.558-4.730)0.374
Peg-IFN-α monotherapy0.588(0.224-1.546)0.282
Treatment time of peg-IFN-α (weeks)1.014(0.992-1.035)0.217
Total duration of peg-IFN-α (weeks)0.999(0.975-1.024)0.9570
Consolidation time < 12 weeks25.636(7.039-93.356)< 0.001
Characteristics at the cessation of peg-IFN-α
Without HBsAg seroconversion5.252(1.684-16.376)0.004
HBsAb, mIU/mL0.952(0.914-0.992)0.018
HBsAb < 35.3 mIU/mL9.705(2.098-44.883)0.004
HBsAb disappeared during the follow-up14.500(1.513-138.972)0.020
ALT level at baseline, IU/L1.011(1.001-1.021)0.127
FibroScan values at baseline (kPa)1.314(0.791-2.183)0.292