Plasma DNA methylation detection for early screening, diagnosis, and monitoring of esophageal adenocarcinoma and squamous cell carcinoma

Table 2 Results of logistic regression analysis (Cox proportional hazard models)

Univariate analysis		Number of patients	OR (95%CI)	P value
Gender	(Male vs female)	210	0.65 (0.32-1.34)	0.568
Age at diagnosis	(≤ 60 vs > 60 years)	210	2.32 (1.45-6.61)	0.021
SCCA	(≤ 3.5 vs > 3.5 U/mL)	210	3.01 (1.54-6.45)	0.023
EPO methylation	(EPO− vs EPO+)	210	7.89 (3.28-18.21)	0.001
SEPT9 methylation	(SEPT9− vs SEPT9+)	210	7.15 (2.86-17.63)	0.001

SCCA: Squamous cell carcinoma antigen; OR: Odds ratio.