Prospective Study
Copyright ©The Author(s) 2024.
World J Gastroenterol. Nov 14, 2024; 30(42): 4532-4543
Published online Nov 14, 2024. doi: 10.3748/wjg.v30.i42.4532
Table 1 Baseline characteristics of the patients, n (%)
Characteristics
Organoid culture successful (n = 9)
Organoid culture unsuccessful (n = 6)
P value
Sex (male)6 (66.7)3 (50.0)0.622
Age (year), mean ± SD60.3 ± 3.569.6 ± 5.40.088
BMI, mean ± SD22.7 ± 1.321.6 ± 1.30.361
Smoking3 (33.3)1 (17.7)0.604
Drinking3 (33.3)1 (17.7)0.604
Tumor size (cm), mean ± SD4.2 ± 0.63.4 ± 0.30.159
Tumor volume (cm3), mean ± SD72.4 ± 24.129.4 ± 8.80.085
Hypertension1 (11.1)2 (33.3)0.525
Diabetes4 (66.7)1 (16.7)0.580
Family of history malignancy3 (33.3)0 (0)0.229
Personal of history malignancy1 (11.1)0 (0)1.000
History of abdominal operation1 (11.1)1 (16.7)1.000
Location, head-neck5 (55.6)4 (66.7)0.608
Clinical TNM staging, III/IV7 (77.8)6 (100.0)0.622
T stage, T3-T46 (66.7)5 (83.3)0.245
N stage, N17 (87.5)4 (66.7)0.538
M stage, M14 (44.4)3 (50.5)1.000
CA19-9 (U/mL), mean ± SD774.4 ± 299.41098.6 ± 382.70.349
CA125, mean ± SD34.9 ± 11.555.3 ± 16.60.514
CEA, mean ± SD4.7 ± 1.14.1 ± 0.70.372
Time from initial diagnosis to puncture biopsy (month), mean ± SD2.5 ± 0.81.0 ± 0.10.526
Ki-67 (%), mean ± SD28.9 ± 7.218.0 ± 3.70.264
IHC, CA19-9 (+)7 (100.0)5 (83.3)
IHC, CEA (+)5 (83.3)4 (100.0)1.000
IHC, P53 (+)5 (71.4)3 (60.0)1.000