Trypsin in pancreatitis: The culprit, a mediator, or epiphenomenon?

doi:10.3748/wjg.v30.i41.4417

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 7, 2024; 30(41): 4417-4438
Published online Nov 7, 2024. doi: 10.3748/wjg.v30.i41.4417

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Figure 1 Trypsin structure and functions. A: N-terminal amino acid sequence of the cationic trypsinogen; B: Schematic of trypsin-mediated activation of other digestive proteases during physiological process of digestion. SP: Signal peptide; TAP: Trypsinogen activation peptide.

Citation: Gukovskaya AS, Lerch MM, Mayerle J, Sendler M, Ji B, Saluja AK, Gorelick FS, Gukovsky I. Trypsin in pancreatitis: The culprit, a mediator, or epiphenomenon? World J Gastroenterol 2024; 30(41): 4417-4438
URL: https://www.wjgnet.com/1007-9327/full/v30/i41/4417.htm
DOI: https://dx.doi.org/10.3748/wjg.v30.i41.4417