Mapping the evolution of liver aging research: A bibliometric analysis

Table 5 The top 5 most cited articles

Rank	Ref.	Year	Journal	Title	JIF	TC	AC
1	Poynard et al[46]	1997	Lancet	Natural history of liver fibrosis progression in patients with chronic hepatitis C. The OBSVIRC, METAVIR, CLINIVIR, and DOSVIRC groups	168.9	2444	87.29
2	Xue et al[47]	2007	Nature	Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas	64.8	1886	104.78
3	Yoshimoto et al[48]	2013	Nature	Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome	64.8	1469	122.33
4	Krizhanovsky et al[71]	2008	Cell	Senescence of activated stellate cells limits liver fibrosis	64.5	1375	80.88
5	Estes et al[72]	2018	Hepatology	Modeling the epidemic of nonalcoholic fatty liver disease demonstrates an exponential increase in burden of disease	14	1250	178.57

JIF: Journal impact factor (2022); TC: Total citations; AC: Average citations.