Amlodipine inhibits the proliferation and migration of esophageal carcinoma cells through the induction of endoplasmic reticulum stress

Figure 3 Amlodipine inhibited esophageal carcinoma cells migration by restraining epithelial-mesenchymal transition. A: Human esophageal carcinoma cells (KYSE-450, TE-1, Eca109, and SKGT-4) were treated with increasing doses of amlodipine (4 μg/mL, 6 μg/mL, and 8 μg/mL) and assessed cell migration at 24 h via Transwell migration assay; B: The Western blot results clearly showed the percentage of mesenchymal marker N-cadherin, epithelial marker E-cadherin, and β-catenin protein in KYSE-450 and Eca109 cells after treatment with amlodipine.