Value of multiple models of diffusion-weighted imaging to predict hepatic lymph node metastases in colorectal liver metastases patients

Table 2 Diagnostic performance of quantitative parameters and nomogram in predicting hepatic lymph node metastases in colorectal liver metastases patient

	AUC	Cut off value	Sensitivity (%)	Specificity (%)	PPV (%)	NPV (%)	Accuracy (%)
Pre-ADC	0.551 (0.436-0.666)	1.70	32.5	82.5	56.5	63.5	61.5
Pre-D	0.648 (0.538-0.758)	1.15	55.0	77.2	62.9	58.1	68.0
Pre-D*	0.592 (0.477-0.707)	2.51	55.0	66.7	53.7	71.0	62.1
Pre-f	0.577 (0.462-0.692)	3.98	70.0	47.5	48.3	64.3	56.7
Pre-DDC	0.770 (0.676-0.865)	1.92	85.0	59.6	59.6	85.0	70.1
Pre-α	0.573 (0.456-0.689)	0.59	62.5	59.6	52.1	69.4	60.8
Post-ADC	0.664 (0.553-0.774)	1.46	75.0	52.6	52.6	75.0	61.9
Post-D	0.581 (0.447-0.681)	1.21	50.0	70.2	54.1	66.7	62.1
Post-D*	0.558 (0.438-0.678)	1.27	85.0	33.3	47.2	76.0	54.6
Post-f	0.521 (0.403-0.638)	3.98	77.5	31.6	44.3	66.7	50.5
Post-DDC	0.739 (0.641-0.838)	2.26	82.5	52.5	55.0	81.1	64.9
Post-α	0.623 (0.509-0.737)	0.65	57.5	70.2	57.5	70.2	65.0
Short axis of largest lymph node before treatment (mm)	0.773 (0.674-0.872)	12	50.0	94.7	87.0	73.0	76.3
Short axis of largest lymph node after treatment (mm)	0.811 (0.724-0.899)	10	52.5	94.7	38.9	74.0	77.3
Nomogram	0.873 (0.803, 0.943)	1.03	82.5	82.5	87.0	76.7	82.5

AUC: Area under the receiver operating characteristic curve; ADC: Apparent diffusion coefficient; NPV: Negative predictive value; PPV: Positive predictive value; DDC: Distributed diffusion coefficient; D: True diffusion coefficient; D*: Pseudo-diffusion coefficient; f: The perfusion fraction; α: Intravoxel water diffusion heterogeneity.