Modulation of host N6-methyladenosine modification by gut microbiota in colorectal cancer

Figure 2 Diet and other environmental factors can provide nutrients for the gut microbiota to metabolize, which can affect the levels of their metabolites (various methyl donors), leading to changes in the level of N6-methyladenosine methylation in the host and ultimately triggering the occurrence of colorectal cancer, as well as the proliferation, metastasis, migration and invasion of tumours. SAM: S-adenosylmethionine; m6A: N6-methyladenosine. Created with BioRender.com (Supplementary material).