Construction and validation of a pancreatic cancer prognostic model based on genes related to the hypoxic tumor microenvironment

Figure 4 Analysis of the risk score model and its prognostic performance of the validation set prognostic model. A: The risk score and survival time distribution of hypoxia-related genes in the verification cohort; B: Kaplan-Meier survival analysis of overall survival (OS) between risk groups in the verification cohort (P < 0.001); C: The verification set receiver operating characteristic (ROC) curves of the risk scoring model for predicting 1-year [area under the curve (AUC) = 0.765], 3-year (AUC = 0.845), and 5-year OS (AUC = 0.809) survival; D: Nomogram calibration curves for predicting 1-year, 3-year, and 5-year OS in the cancer genome atlas-pancreatic adenocarcinoma cohort; E: ROC curves for the prediction of survival based on the risk score and other variables (M, N, T, age, pathologic stage, residual tumor, neoplasm histologic grade, and LASSO-derived risk score); F: Nomogram of the risk score and traditional prognostic factors. AUC: Area under the curve.