Correlation between the neuroendocrine axis, microbial species, inflammatory response, and gastrointestinal symptoms in irritable bowel syndrome

Table 4 Comparison of inflammatory factor levels between different phenotypes of irritable bowel syndrome

	IBS-D	IBS-C	IBS-M	IBS-U	F	P value
Number of cases	36	24	15	5	-	-
IL-6 (ng/L)	18.37 ± 4.76	22.05 ± 6.34	19.92 ± 4.98	20.68 ± 5.59	3.801	0.285
IL-8 (ng/L)	45.80 ± 12.56	59.23 ± 17.28	53.91 ± 15.03	49.77 ± 13.94	1.917	0.477
IL-10 (ng/L)	19.43 ± 7.82	28.15 ± 5.94	25.67 ± 6.32	22.08 ± 6.51	1.253	0.253

IBS-D: Diarrhea predominant IBS; IBS-C: Constipation predominant IBS; IBS-M: Mixed-type IBS; IBS-U: Unspecified-type IBS.