Correlation between the neuroendocrine axis, microbial species, inflammatory response, and gastrointestinal symptoms in irritable bowel syndrome

doi:10.3748/wjg.v30.i35.3985

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Sep 21, 2024 (publication date) through Sep 13, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 21, 2024; 30(35): 3985-3995
Published online Sep 21, 2024. doi: 10.3748/wjg.v30.i35.3985

Table 2 Comparison of neuroendocrine axis indicators between different phenotypes of irritable bowel syndrome

	IBS-D	IBS-C	IBS-M	IBS-U	F value	P value
Number of cases	36	24	15	5	-	-
ACTH (ng/mL)	16.45 ± 2.41	16.33 ± 2.39	17.48 ± 2.37	16.78 ± 2.54	1.315	0.274
COR (pg/mL)	191.37 ± 20.11	189.81 ± 20.45	190.23 ± 20.47	189.46 ± 20.73	3.552	0.338
5-HT (ng/mL/mg)	0.52 ± 0.24	0.58 ± 0.34	0.54 ± 0.21	0.57 ± 0.246	0.452	0.638

IBS-D: Diarrhea predominant IBS; IBS-C: Constipation predominant IBS; IBS-M: Mixed-type IBS; IBS-U: Unspecified-type IBS; ACTH: Adrenocorticotropic hormone; COR: Cortisol; 5-HT: 5-hydroxytryptamine.

Citation: Zhang X, Jin WW, Wang HG. Correlation between the neuroendocrine axis, microbial species, inflammatory response, and gastrointestinal symptoms in irritable bowel syndrome. World J Gastroenterol 2024; 30(35): 3985-3995
URL: https://www.wjgnet.com/1007-9327/full/v30/i35/3985.htm
DOI: https://dx.doi.org/10.3748/wjg.v30.i35.3985