B-cell-specific signatures reveal novel immunophenotyping and therapeutic targets for hepatocellular carcinoma

Figure 2 Cell-to-cell communication in hepatocellular carcinoma. A: Cellular map illustrates the distribution and abundance of various cell subgroups within hepatocellular carcinoma (HCC); B: Pie chart displays the accurate cell counts of each cell subgroup in HCC; C: Bar graph demonstrates the proportional distribution of each cell subgroup among individual HCC patients; D: Heatmap exhibits the number of gene pairs interacting between cell groups; E: Using cell chat, the interaction probability between specific cell groups and other cell groups is depicted; F: Using cell chat, the interaction probability is delineated between B cells as donors and specific gene pairs of other cells; G: Using cell chat, the interaction probability is delineated between B cells as recipients and specific gene pairs of other cells; H: Volcano plot showcases the differentially expressed genes within B cells. Red indicates fold change > 1.5 and FDR < 0.05; green indicates fold change < 1.5 and FDR < 0.05. LIHC: Liver hepatocellular carcinoma; NK: Nature kill; DC: Dendritic cells; HLA: Human leukocyte antigen.