B-cell-specific signatures reveal novel immunophenotyping and therapeutic targets for hepatocellular carcinoma

Figure 1 Detailed flowchart illustrates the identification and validation of the prognostic model associated with B-cell-related genes. HCC: Hepatocellular carcinoma; TCGA: The Cancer Genome Atlas; BRGs: B-cell-related genes; TISCH2: Tumor Immune Single-Cell Hub 2; ROC: Receiver operating characteristic; KEGG: Kyoto Encyclopedia of Genes and Genomes; GO: Gene Ontology; GSEA: Gene set enrichment analysis; LASSO: Least absolute shrinkage and selection operator; ICGC: International Cancer Genome Consortium; PCA: Principal component analysis; tSNE: T-distributed stochastic neighbor embedding; GSE: Gene Expression Omnibus Series.