Clinical features of gastroesophageal reflux disease and erosive esophagitis: Insights from patients undergoing esophagogastroduodenoscopy in resource-limited Ethiopia

Table 5 Factors associated with the severity of erosive esophagitis in patients with erosive esophagitisat Tikur Anbesa specialized hospital and Adera medical and surgical center during the study period

Variables	Severity of EE
	LA-A	LA-B/C/D	COR (95%CI)	P value	AOR (95%CI)	P value
Age of the study participants
Less than 50	107	32	1
50 and above	51	31	2.032 (1.12-3.689)	0.02	2.331 (1.169-4.649)	0.016a
Diabetes mellitus
None	150	56	1
Present	8	7	2.344 (0.812-6.764)	0.115	1.826 (0.455-7.330)	0.396
NSAID use
None	152	56	1
Present	6	7	3.167 (1.020-9.829)	0.046	1.681 (0.409-6.915)	0.472
Typical symptoms
None	80	40	1.696 (0.93-3.091)	0.085	1.800 (0.909-3.563)	0.092
Present	78	23	1
UGIB
None	141	48	1
Present	17	15	2.592 (1.203-5.585)	0.015	2.603 (1.111-6.098)	0.028a
Helicobacter pylori antigen
Positive	29	5	1		-	-
Negative	88	33	2.175 (0.777-6.092)	0.139	-	-
Bile acid gastropathy
None	151	57	1
Present	7	6	2.271 (0.732-7.045)	0.156	1.812 (0.521-6.299)	0.350
Duodenal ulcer
None	145	51	1
Present	13	12	2.624 (1.125-6.122)	0.026	2.405 (0.918-6.301)	0.074
Duodenopathy/duodenitis
None	147	52	1
Present	11	11	2.827 (1.157-6.908)	0.023	3.517 (1.259-9.824)	0.016a
Antral gastritis/gastropathy
None	111	52	2.002 (0.960-4.172)	0.064	2.229 (0.997-4.986)	0.051
Present	47	11	1
Pan gastritis/gastropathy
None	147	62	4.639 (0.586-36.712)	0.146	8.256 (0.967- 70.531)	0.054
Present	11	1	1

^aP < 0.05, and it is statistically significant.

EE: Erosive esophagitis; COR: Common odds ratio; AOR: Adjusted odds ratio; 95%CI: 95% confidence interval; LA: Los Angeles; NSAID: Nonsteroidal anti-inflammatory drug; UGIB: Upper gastrointestinal bleeding.