Pan-immune-inflammation value as a prognostic biomarker for colon cancer and its variation by primary tumor location

Figure 3 The relationship between pan-immune-inflammation value and disease-free survival in patients with left-sided colon cancer and right-sided colon cancer. A: In the left-sided colon cancer group, pan-immune-inflammation value (PIV)-high patients had a worse disease-free survival (DFS) than that of PIV-low patients; B: The generalized boosted regression model evaluated the relative impact of systemic inflammatory response markers on DFS, with PIV showing the highest relative influence among systemic inflammatory response markers in left-sided colon cancer patients; C: In the right-sided colon cancer group, there was no significant difference in DFS between PIV-high and -low. LCC: Left-sided colon cancer; RCC: Right-sided colon cancer; PIV: Pan-immune-inflammation value; NLR: Neutrophil-to-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio; SII: Systemic immune-inflammation index; DFS: Disease-free survival.