Role of gut microbiota in Crohn’s disease pathogenesis: Insights from fecal microbiota transplantation in mouse model

Table 2 Clinical data of 5 Crohn’s disease patients who served as stool specimen donors, n (%)

Patient characteristics	Quantity (percentage)
Sex
Female	1 (20.0)
Male	4 (80.0)
Age (years old)
≤ 16	0 (0.0)
17-40	2 (40.0)
> 40	3 (60.0)
Course of the disease (years)
< 1	1 (20.0)
1-5	3 (60.0)
> 5	1 (20.0)
Onset or recurrence of diseases
Onset	0 (0.0)
Recurrence	5 (100.0)
WBC count (× 109)
< 10.0	2 (40.0)
≥ 10.0	3 (60.0)
HGB (g/L)
< 100.0	0 (0.0)
≥ 100.0	5 (100.0)
ALB (g/L)
< 30.0	3 (60.0)
≥ 30.0	2 (40.0)
BMI (kg/m2)
< 18.5	2 (40.0)
≥ 18.5	3 (60.0)

This table succinctly presents the demographic and clinical characteristics of the 5 stool specimen donor patients included in this study. Among them, 4 were male (80.0%) and 1 was female (20.0%). Age distribution showed that all patients were over 17 years old, 2 patients (40.0%) were between 17 and 40 years old, and the remaining 3 patients (60.0%) were over 40 years old. In terms of disease course, only 1 patient (20.0%) had a disease course within 1 year, 3 patients (60.0%) had a disease course between 1 and 5 years, and 1 patient (20.0%) had a disease course exceeding 5 years. All 12 patients had recurrent disease. Laboratory test results showed that the white blood cell (WBC) count of 2 people (40.0%) was lower than 10.0 × 10⁹, and the WBC count of 3 people (60.0%) reached 10.0 × 10⁹ and above. All 5 patients (100.0%) had hemoglobin levels of 100 g/L and above. Three patients (60.0%) had serum ALB levels below 30 g/L, and the remaining 2 patients (40.0%) had serum albumin levels of 30 g/L or higher. Height and weight measurements showed that 2 patients (40.0%) had a body mass index (BMI) value lower than 18.5 kg/m², and the remaining 3 patients (60.0%) had a BMI value equal to or exceeding 18.5 kg/m². WBC: White blood cell; HGB: Hemoglobin; ALB: Albumin; BMI: Body mass index.