Fanlian Huazhuo Formula alleviates high-fat diet-induced non-alcoholic fatty liver disease by modulating autophagy and lipid synthesis signaling pathway

Figure 9 Fanlian Huazhuo Formula group reduced apoptosis in mice induced by high-fat diet. A: Protein expression levels of Bax and Bcl-2 in mice liver (n = 3); B: Hepatic mRNA expression levels of Bax and Bcl-2 in mice liver (n = 3); C: Representative images and the quantification of immunohistochemistry for cleaved caspase-3 in mice liver, magnification 400 × (n = 3); D: Representative images and quantification of TUNEL staining of liver in mice, 200 × (n = 3). Data are presented as mean ± SE. ^aP < 0.05 vs NC group, ^cP < 0.05 vs MOD group. NC: Negative control group; MOD: Model group; FNBT: Fenofibrate group; FLHZF-L: Low dose of Fanlian Huazhuo Formula group; FLHZF-H: High dose of Fanlian Huazhuo Formula group.