Fanlian Huazhuo Formula alleviates high-fat diet-induced non-alcoholic fatty liver disease by modulating autophagy and lipid synthesis signaling pathway

Figure 4 Fanlian Huazhuo Formula group reduced oxidative damage in vivo and in vitro. A: Cell reactive oxygen species (ROS) content with Fanlian Huazhuo Formula group treatment in HepG2 cells induced by free fatty acid (n = 3); B: Quantitative result of cell ROS content (n = 3); C: Serum levels of malondialdehyde (n = 8); D: Serum levels of superoxide dismutase (n = 8); E: Serum levels of glutathione peroxidase (n = 8). Data are presented as mean ± SE. ^aP < 0.05 vs NC group, ^bP < 0.01 vs NC group, ^cP < 0.05 vs MOD group, ^dP < 0.01 vs MOD group. ROS: Reactive oxygen species; MDA: Malondialdehyde; SOD: Superoxide dismutase: GSH-Px: Glutathione peroxidase; NC: Negative control group; MOD: Model group; FNBT: Fenofibrate group; FLHZF-L: Low dose of Fanlian Huazhuo Formula group; FLHZF-H: High dose of Fanlian Huazhuo Formula group.