Fanlian Huazhuo Formula alleviates high-fat diet-induced non-alcoholic fatty liver disease by modulating autophagy and lipid synthesis signaling pathway

Figure 2 Effects of Fanlian Huazhuo Formula group on symptoms associated with nonalcoholic fatty liver disease mice. A: Flow chart of animal experiment protocol; B: Body weight of mice once a week for 10 weeks (n = 8); C: Weight change (pre-treatment weight minus post-treatment weight) of mice (n = 8); D: Liver index of nonalcoholic fatty liver disease (NAFLD) mice (n = 8); E: Fat index of NAFLD mice (n = 8); F: Representative images of livers after 10 weeks intervention in mice. Data are presented as mean ± SE. ^bP < 0.01 vs NC group, ^cP < 0.05 vs MOD group, ^dP < 0.01 vs MOD group. NC: Negative control group; MOD: Model group; FNBT: Fenofibrate group; FLHZF-L: Low dose of Fanlian Huazhuo Formula group; FLHZF-H: High dose of Fanlian Huazhuo Formula group.