SLC6A14 promotes ulcerative colitis progression by facilitating NLRP3 inflammasome-mediated pyroptosis

Figure 1 SLC6A14 in ulcerative colitis tissues. A: Hematoxylin and eosin staining and immunohistochemical (IHC) analysis of SLC6A14 expression in normal and ulcerative colitis (UC) tissues (magnification, × 200; scale bar = 100 μm); B: SLC6A14 mRNA levels were assessed by real-time polymerase chain reaction in UC (n = 55) and normal tissues (n = 29); C and D: SLC6A14 protein levels in UC (n = 55) and normal tissue samples (n = 29); E: Quantification of the IHC scores for SLC6A14 expression; F and G: NLRP3 protein levels in UC (n = 55) and normal tissue samples (n = 29); H: Association between SLC6A14 and NLRP3 levels in human colonic tissues. The data represent the means ± SD. ^aP < 0.01 vs the controls. UC: Ulcerative colitis.