Calculus bovis inhibits M2 tumor-associated macrophage polarization via Wnt/β-catenin pathway modulation to suppress liver cancer

Figure 4 Differentially expressed genes between Calculus bovis-treated group and control group (q < 0. 05 and log2FlodChange > 0) after transcriptome sequences were analyzed by bioinformatics. A: Differential gene volcano plot between the Calculus bovis (CB)-treated and control groups; B: Histogram of Gene Ontology enrichment results of differentially expressed mRNAs in the CB-treated and control groups (top 10); C: Bubble plots of Kyoto Encyclopedia of Genes and Genomes enrichment results of differentially expressed mRNAs in the CB-treated and control groups (top 20); D: Heatmap of selected genes involved in the Wnt pathway.