Calculus bovis inhibits M2 tumor-associated macrophage polarization via Wnt/β-catenin pathway modulation to suppress liver cancer

Figure 3 Cyberpharmacological study on anti-liver cancer mechanism of active components of Calculus bovis based on UPLC-Q-TOF-MS analysis. A: Intersection plot of potential targets of Calculus bovis (CB) and liver cancer targets; B: Component-target-disease interaction network of CB against liver cancer. The purple quadrilaterals represent the active components of CB; C: Protein-protein interaction network; D: Gene Ontology function analysis of CB against liver cancer; E: Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis of CB against liver cancer; F: Minimum binding energy of the active components of CB with core target proteins; G: Molecular docking diagram of some active components.