Leech Poecilobdella manillensis protein extract ameliorated hyperuricemia by restoring gut microbiota dysregulation and affecting serum metabolites

Figure 8 Correlation analysis between the gut microbiota and metabolites from hyperuricemia and leech Poecilobdella manillensis total protein extract groups. The R values are represented by gradient colors, where purple cells indicate positive correlations and green cells indicate negative correlations, respectively. Statistical significance is denoted as follows: ^aP < 0.05, ^bP < 0.01, ^cP < 0.001.