Targeted metabolomics study of fatty-acid metabolism in lean metabolic-associated fatty liver disease patients

doi:10.3748/wjg.v30.i27.3290

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Jul 21, 2024; 30(27): 3290-3303
Published online Jul 21, 2024. doi: 10.3748/wjg.v30.i27.3290

Table 1 Ion pairs of analytes and internal standards

ID	Q1	Q3	DP	CE	CXP
AEA-d8	356.100	294.000	64.94	19.09	18.93
AEA	348.000	62.000	56.00	42.00	10.00
2-AG	379.000	287.400	163.86	20.05	13.09
OEA	326.400	309.200	195.32	21.31	29.01
OEA-d4	330.600	66.100	132.66	21.55	12.58
LEA	324.400	62.100	130.26	17.76	11.28
PEA	300.300	62.100	124.00	19.83	10.20
LEA-d4	328.100	66.000	133.80	20.98	8.59
1-LG	355.300	338.400	32.21	10.73	18.49
1-OG	357.300	339.300	145.00	13.20	24.00
1-PG	331.200	313.500	155.00	12.70	19.00
LA	325.200	279.100	-10.11	-8.72	-25.70
OA	327.200	281.300	-47.00	-10.50	-10.00
PA	301.200	255.200	-58.00	-14.00	-15.00
AA	303.100	259.000	-73.90	-16.14	-13.02
OA-d9	336.300	290.300	-14.34	-9.32	-7.94

1-LG: 1-linoleoyl glycerol; 1-OG: 1-oleoyl glycerol; 1-PG: 1-palmitoyl glycerol; 2-AG: 2-arachidonoylglycerol; AA: Arachidonic acid; AEA: Arachidonoylethanolamide; AEA-d8: Deuterated arachidonoylethanolamide; LA: Linoleic acid; LEA: Linoleoylethanolamide; LEA-d4: Deuterated linoleoylethanolamide; OA: Oleic acid; OA-d9: Deuterated oleic acid; OEA: Oleoylethanolamide; OEA-d4: Deuterated oleoylethanolamide; PA: Palmitic acid; PEA: Palmitoylethanolamide.

Citation: Sun PQ, Dong WM, Yuan YF, Cao Q, Chen XY, Guo LL, Jiang YY. Targeted metabolomics study of fatty-acid metabolism in lean metabolic-associated fatty liver disease patients. World J Gastroenterol 2024; 30(27): 3290-3303
URL: https://www.wjgnet.com/1007-9327/full/v30/i27/3290.htm
DOI: https://dx.doi.org/10.3748/wjg.v30.i27.3290