Predicting hepatocellular carcinoma: A new non-invasive model based on shear wave elastography

Table 2 Both univariable and multivariable logistic regression approaches to assess the probability of liver cancer in the experimental cohort (n = 720)

Variable	Univariable		Multivariable
	Odds ratio	P value	Odds ratio	P value
Clinical data
Age (years)	1.00 (0.99, 1.02)	0.352
Sex (%)	0.85 (0.57, 1.26)	0.424
Body mass index (kg/m2)	1.01 (0.96, 1.06)	0.678
Nationality (%)	0.66 (0.27, 1.61)	0.364
History of tumor (%)	1.50 (0.79, 2.82)	0.213
Laboratory data
ALT (IU/L)	1.00 (0.99, 1.00)	0.306
AST (IU/L)	1.00 (0.99, 1.00)	0.299
GGT (IU/L)	1.00 (0.99, 1.00)	0.249
Prothrombin time (s)	1.00 (0.93, 1.24)	0.328
INR	2.94 (0.50, 17.38)	0.235
PLT (109/L)	1.00 (0.99, 1.00)	< 0.001	1.00 (0.99, 1.00)	< 0.001
Albumin (g/L)	1.00 (0.97, 1.05)	0.780
Total bilirubin (µmol/L)	1.01 (0.98, 1.04)	0.638
Ultrasonic data
Number (%)	0.61 (0.42, 0.89)	0.009	0.61 (0.40, 0.95)	0.027
Diameter (cm)	1.01 (0.96, 1.07)	0.628
Shape (%)	0.76 (0.55, 1.06)	0.102
Echo (%)	1.38 (0.98, 1.94)	0.065
Edge (%)	1.56 (1.11, 2.17)	0.010
Cirrhosis (%)	3.04 (2.03, 4.57)	< 0.001
Blood (%)	2.50 (1.79, 3.50)	< 0.001	2.51 (1.72, 3.67)	< 0.001
Emax of the tumors (m/s)	2.86 (2.10, 3.91)	< 0.001	2.08 (1.50, 2.89)	< 0.001
Emean of the tumors (m/s)	3.95 (2.60, 6.01)	< 0.001
Emax of the periphery of tumors (m/s)	5.72 (3.51, 9.34)	< 0.001
Emean of the periphery of tumors (m/s)	5.84 (3.54, 9.63)	< 0.001	2.70 (1.54, 4.73)	0.001

The data enclosed between parenthesis represents the intervals of confidence at 95%. ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; GGT: G-glutamyl transferase; PLT: Platelet count; Emax: Maximal elasticity; Emean: Mean elasticity.