Thymoquinone affects hypoxia-inducible factor-1α expression in pancreatic cancer cells via HSP90 and PI3K/AKT/mTOR pathways

Figure 4 Effects of Thymoquinone on cell cycle of normal pancreatic duct epithelial cells and PANC-1 cells under hypoxia condition. A: The cell cycle changes of normal pancreatic duct epithelial (hTERT-HPNE) cells and PANC-1 cells in normal control (NC) group and Thymoquinone (TQ) group were analyzed by flow cytometry; B: Statistical analysis of cell cycle changes of hTERT-HPNE cells in NC group and TQ group under hypoxia condition; C: Statistical analysis of cell cycle changes of PANC-1 cells in NC group and TQ group under hypoxia condition. ^aP < 0.01. NC: Normal control; TQ: Thymoquinone; hTERT-HPNE: Normal pancreatic duct epithelial.