Thymoquinone affects hypoxia-inducible factor-1α expression in pancreatic cancer cells via HSP90 and PI3K/AKT/mTOR pathways

Figure 3 Effects of Thymoquinone on invasion of normal pancreatic duct epithelial and PANC-1 cells under hypoxia condition (Transwell assay). A: The invasion ability of normal pancreatic duct epithelial (hTERT-HPNE) cells and PANC-1 cells in normal control (NC) group and Thymoquinone (TQ) group were detected by Transwell assay under hypoxia condition (× 100); B: Statistical analysis of invasion ability of hTERT-HPNE cells and PANC-1 cells in NC group and TQ group under hypoxia condition. ^aP < 0.01. NC: Normal control; TQ: Thymoquinone; hTERT-HPNE: Normal pancreatic duct epithelial.