Thymoquinone affects hypoxia-inducible factor-1α expression in pancreatic cancer cells via HSP90 and PI3K/AKT/mTOR pathways

Figure 2 Effects of Thymoquinone on migration ability of normal pancreatic duct epithelial and PANC-1 cells under hypoxia condition. A: The migration ability of normal pancreatic duct epithelial (hTERT-HPNE) cells and PANC-1 cells in normal control (NC) group and Thymoquinone (TQ) group was detected by cell scratch tassay under hypoxia condition; B: Statistical analysis of migration ability of hTERT-HPNE cells and PANC-1 cells in NC group and TQ group under hypoxia condition (cell scratch tassay); C: The migration ability of hTERT-HPNE cells and PANC-1 cells in NC group and TQ group were detected by Transwell assay under hypoxia condition (× 100); D: Statistical analysis of migration ability of hTERT-HPNE cells and PANC-1 cells in NC group and TQ group under hypoxia condition (Transwell assay). ^aP < 0.01. NC: Normal control; TQ: Thymoquinone; hTERT-HPNE: Normal pancreatic duct epithelial.