Effects of proton pump inhibitors on inflammatory bowel disease: An updated review

doi:10.3748/wjg.v30.i21.2751

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Jun 7, 2024 (publication date) through Mar 2, 2025

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Jun 7, 2024; 30(21): 2751-2762
Published online Jun 7, 2024. doi: 10.3748/wjg.v30.i21.2751

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Figure 1 Mother nucleus structure of proton pump inhibitors. Omeprazole (R₁: OCH₃, R₃: OCH₃, R₂R₄: CH₃), lansoprazole (R₁: H, R₃: CF₃CH₂O, R₂R₄: CH₃), pantoprazole (R₁: F₂CHO, R₂R₃: CH₂O, R₄: H), rabeprazole (R₁R₄: H, R₂: CH₃, R₃: CH₃-O-CH₂-CH₂-CH₂O), ilaprazole (R₁: pyrrole, R₂: CH₃, R₃: OCH₃, R₄: H). Esomeprazole is the S-isomer of omeprazole and dexlansoprazole is the R-isomer of lansoprazole.

Citation: Liang Y, Meng Z, Ding XL, Jiang M. Effects of proton pump inhibitors on inflammatory bowel disease: An updated review. World J Gastroenterol 2024; 30(21): 2751-2762
URL: https://www.wjgnet.com/1007-9327/full/v30/i21/2751.htm
DOI: https://dx.doi.org/10.3748/wjg.v30.i21.2751