Long-term prognosis and its associated predictive factors in patients with eosinophilic gastroenteritis

Table 2 Clinical characteristics and intergroup comparisons

	Non glucocorticoid treatment (n = 12)	Glucocorticoid treatment (n = 43)	P value	Non-glucocorticoid dependent (n = 22)	Glucocorticoid dependent (n = 21)	P value
Sex (female)	8 (66.7)	23 (53.5)	0.519	10 (45.5)	13 (61.9)	0.364
Age (yr)2	44.00 [27.75, 48.75]	36.00 [25.00, 50.00]	0.838	36.00 [26.00, 53.25]	36.00 [25.00, 48.00]	0.780
BMI (kg/m2)1	23.43 ± 2.84	23.24 (4.25)	0.888	24.51 (4.55)	21.85 (3.50)	0.041a
Disease duration (mo)	2.00 [1.00, 10.00]	7.00 [1.00, 41.00]	0.223	3.00 [1.00, 15.75]	11.00 [4.00, 60.00]	0.056b
Allergic history	2 (16.7)	16 (37.2)	0.298	8 (36.4)	8 (38.1)	1.000
Symptoms
Abdominal pain	11 (91.7)	38 (88.4)	1.000	19 (86.4)	19 (90.5)	1.000
Diarrhea	8 (66.7)	26 (60.5)	0.750	12 (54.5)	14 (66.7)	0.537
Vomiting	3 (25.0)	23 (53.5)	0.108	12 (54.5)	11 (52.4)	1.000
Weight loss	10 (83.3)	26 (60.5)	0.183	14 (63.6)	12 (57.1)	0.760
Hp infection	5 (5/11, 45.5)	11 (11/39, 28.2)	0.297	6 (6/20, 30.0)	5 (5/19, 26.3)	1.000
Klein classification
Mucosal type	6 (50.0)	22 (51.2)	1.000	11 (50.0)	11 (52.4)	0.298
Muscular type	2 (16.7)	7 (16.3)		2 (9.1)	5 (23.8)
Serosal type	4 (33.3)	14 (32.6)		9 (40.9)	5 (23.8)
EOS (× 109/L)2	0.76 [0.51, 2.32]	1.48 [0.95, 4.00]	0.124	2.46 [1.13, 3.96]	1.01 [0.48, 3.99]	0.065b
IgE (KU/L)2	54.50 [23.77, 629.75]	166.00 [72.90, 298.00]	0.406	234.00 [118.00, 343.25]	118.00 [67.10,191.00]	0.082b
Elevated IgE (> 60)	5 (5/10, 50.0)	33 (33/36, 86.8)	0.022a	17 (17/20, 85.0)	16 (16/18, 88.9)	1.000
Duodenum involvement	7 (7/11, 63.6)	33 (33/43, 76.7)	0.448	15 (68.2)	18 (85.7)	0.281
Bulb	5 (5/11, 45.5)	21 (21/43, 48.8)	1.000	9 (40.9)	13 (61.9)	0.227
Post-bulb	1 (1/11, 9.1)	15 (15/43, 34.9)	0.144	11 (50.0)	4 (19.0)	0.055b
Descending part	3 (3/11, 27.3)	27 (27/43, 62.8)	0.046a	12 (54.5)	15 (71.4)	0.347
Duodenum endoscopic features
Hyperaemia	6 (6/11, 54.5)	25 (25/43, 58.1)	1.000	14 (63.6)	11 (52.4)	0.543
Erosion	3 (3/11, 27.3)	10 (10/43, 23.3)	1.000	4 (18.2)	6 (28.6)	0.488
Ulcer	1 (1/11, 9.1)	4 (4/43, 9.3)	1.000	0 (0.0)	4 (19.0)	0.048a

¹mean ± SD.

²Mean[Q1, Q3].

^aP < 0.05.

^bP < 0.10.

Hp: Helicobacter pylori; EOS: Eosinophil count; IgE: Serum immunoglobin E; BMI: Body mass index.