HepG2.2.15-derived exosomes facilitate the activation and fibrosis of hepatic stellate cells

Figure 2 The impact of HepG2. 2.15-derived exosomes on the activation of LX2 cells. A: Display of LX2 cells in a normal culture environment, showing red lipid droplets; B: Illustration of LX2 cells co-cultured with HepG2-exo. Similar to the normal culture, red lipid droplets are present; C: Depiction of LX2 cells co-cultured with WRL68-exo. Also maintains presence of red lipid droplets; D: Representation of LX2 cells when co-cultured with HepG2.2.15-exo. Notably, after 24 h of oil red staining, the red lipid droplets disappear, indicating a significant change caused by the HepG2.2.15-exo. Magnification Times: 20 ×.